Teams chasing league titles have a shot at glory this weekend in matches that could reshuffle the top spots in leagues worldwide.
Serie A fans are treated to the Derby della Lanterna this weekend. Despite their low table status, Sampdoria are favourites at home to seventh placed Genoa. Of their 50 Seria A meetings so far the Blucerchiati have won 18 and Genoa 10.
Everton host Aston Villa in Premier League action. Inspired by their recent away win over Arsenal and draw at home to Manchester United, Villa will be eager to keep gaining ground on the leaders. Unbeaten at home in four games, an Everton win will lock The Toffees on points with Villa on the league table. Take care - and predict wisely on this one.
In the Bundesliga, Hertha travel to Schalke 04. With second place Bayern Munich facing league leader's Hoffenheim this week, third place Hertha will be desperate to gain ground on the top two. A Hertha win will net backers a hefty 85 points.
Caen host Rennes in France's Ligue 1. Undefeated in six games, Les Rouges et Noirs are solid favourites. A Rennes win nets you 54 points while a successful Caen backing carries a 74-point reward.
Columbia's Copa Mustang is well into the group stage. In Group B, second place Junior take on group leaders America. With only one team advancing to the final playoffs from each group and only three games left, this could be Junior's last chance to overcome America. Junior is a longshot at 87 points, while an America win nets backers 30 points.
Match of the Week
The last match off the season in the Brasileirão brings with it tension and excitement for Sao Paulo and Gremio fans. Sao Paulo travel to seventh placed Goias this week and loss for the Tricolor Paulista could crown Gremio champions.
Sao Paulo are hot favourites but Goias will relish the chance to rob the current Brasileirao champions of another crown. Goias backers could net a giant 86 points, while a sensible Sao Paulo win is worth 29 points.
Leaders, will your nerves hold and talent shine? Contenders, is this your week to overthrow the old dogs? We will soon find out.