Big duels in Manchester and Melbourne
© Getty Images

FIFA.com takes a weekly look at some of the prominent games on the upcoming round of the FIFA World Leagues Predictor.

Match of the week
Manchester United-Arsenal (England)
The Red Devils and the Gunners have a huge incentive to win their Old Trafford showpiece: the victorious team will finish Round 17 of the Premier League at its summit, while a draw will allow Chelsea the opportunity to reclaim pole position. That is currently occupied by Arsene Wenger’s team, although Sir Alex Ferguson’s charges are only a point behind with a game in hand. Two men who could have a decisive impact on the outcome are United winger Nani and Arsenal playmaker Samir Nasri, both of whom have been in resplendent form of late. Can United hold on to the league’s only undefeated record at home to a side who have proven most formidable when on the road this season?

Contenders square off
Juventus-Lazio (Italy)
Hot in pursuit of leaders AC Milan, second-placed Lazio - who last weekend stunned defending champions Inter Milan with a comfortable 3-1 win - and third-placed Juventus are set to meet. An away victory would take the Rome giants six points clear of their opponents, while a home success would be enough for Juve to leapfrog their guests into second.

Underachievers versus overachievers
Hamburg-Bayer Leverkusen (Germany)
Bayer Leverkusen have exceeded expectations this season. However, 11 points off the pace in third, they need to extend their six-match unbeaten run if they are to likely avoid falling further behind leaders Borussia Dortmund. Next up for Bayer is a trip to Hamburg, who find themselves down in mid-table after losing three of their last four. HSV have nevertheless taken ten points from their last four home matches.

Strugglers collide
Brest-Montpellier (France)
Since hitting the Ligue 1 summit in Round 11, Brest find themselves down in sixth just five matchdays later. Meanwhile Montpellier are in tenth - their second-worst position this season. With only one point separating the two sides in the standings, both will be desperate to ease their troubles.

The Melbourne derby
Melbourne Heart-Melbourne Victory (Australia)
John van’t Schip and Ernie Merrick will look to mastermind a win in the A-League’s only fixture that involves teams from the same city. The Heart, in their maiden season, triumphed 2-1 in the inaugural derby on 8 October, and though they currently head their new rivals by a point, the Victory have two games in hand.

Round 16 games (11-13 December)
Vllaznia Shkoder-Skenderbeu (Albania)
Estudiantes-Arsenal (Argentina)
Melbourne Heart-Melbourne Victory (Australia)
Manchester United-Arsenal (England)
Brest-Montpellier (France)
Juventus-Lazio (Italy)
Hamburg-Bayer Leverkusen (Germany)
Golden Arrows-Mamelodi Sundowns (South Africa)
Sporting Gijon-Levante (Spain)
Lucerne-FC Zurich (Switzerland)